Rogers and Kesner (2003) Aim: To investigate the role of acetylcholine on memory encoding and memory retrieval. Method: It was a laboratory experiment using rats. Rats were trained to learn a simple maze, but before the memories could be learned well-enough to be transferred from short-term memory to long-term memory, the rats were divided into groups and injected with drugs: Group 1 was injected with scopolamine, which is known to block the reception of acetylcholine by the post-synaptic neurons. This means that acetylcholine, a neurotransmitter expected to help form memories, cannot travel from one neuron to another. This was the no acetylcholine condition. Group 2 was injected with physostigmine, a drug that blocks cholinesterase, which is what cleans up the acetylcholine from receptor proteins on the post-synaptic neurons, returning the neurons to their resting potential, where no nerve impulse is being sent. Therefore the acetylcholine continued to act. This was the h...